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Perinatal Hepatitis B Program

Hepatitis B: A Serious Health Problem

The acute and chronic consequences of hepatitis B virus (HBV) infection are major health problems in the United States. It is estimated that this country currently contains a pool of 1 to 1.25 million infectious carriers of HBV. Preventing HBV transmission during early childhood is important because of the likelihood of chronic HBV infection and chronic liver disease that occurs when children less than five years of age become infected.

The transmission of HBV from mother to infant is very efficient. If the mother is positive for both hepatitis B surface antigen (HBsAg) and hepatitis B e antigen, 70 - 90 percent of infants will become infected if not given hepatitis B immune globulin (HBIG) and hepatitis B vaccine soon after birth. The risk of perinatal transmission is about 20 percent if the mother is positive for HBsAg only. Up to 90 percent of these infected infants will become HBV carriers. An estimated 15 - 25 percent of these carriers will ultimately die of liver failure secondary to chronic active hepatitis, cirrhosis, or primary hepatocellular carcinoma.

Recommendations, resources, and general information from the Immunization Action Coalition (IAC)

The Alabama Perinatal Hepatitis B Program

The Alabama Perinatal hepatitis B Program is a case management system that serves public and private HBsAg-positive maternity patients throughout Alabama. State Coordinators work closely with private physicians and their nursing staff, as well as county health departments, to ensure that patients are informed about HBV. Efforts are made to identify and screen all household and sexual contacts for HBsAg and antibodies to HBV and to give hepatitis B vaccine if indicated. The case management system extends to the infants of HBsAg-positive patients to ensure they receive proper biologicals at birth and at the recommended times in infancy, as well as ensuring that titers are drawn following completion of the three-dose series of hepatitis B vaccine.

Services Provided by the Alabama Perinatal Hepatitis B Program

The following services are provided at no charge to the patient or physician:

  • Patient education and counseling.
  • Identification and testing of household and sexual contacts including vaccination with hepatitis B vaccine if indicated.
  • Notification of the birth hospital about impending birth to ensure that HBIG and hepatitis B vaccine are available for the newborn in the first 12 hours of life.
  • Notification of the medical provider of the infant's birth and the hepatitis B vaccination schedule.
  • Follow-up of the infant to ensure the hepatitis B vaccine series is completed and the infant is tested for antibodies to hepatitis B to ensure the baby is protecte.

Prevent Perinatal hepatitis B

For referral and case management of HBsAg-positive maternity patients, contact the Perinatal hepatitis B Coordinator in your area, or call the Immunization Division at 1-800-469-4599.

Northeast Region

North Central Region

Anita Collier, RN

Rebecca Warren, RN, MSN

Marshall County Health Department

Tuscaloosa Co Health Department

P.O. Drawer 339

2350 Hargrove Road East

Guntersville, Alabama  35976

Tuscaloosa, Alabama  35405

Telephone:  (256) 582-2390

Telephone:  (205) 554-4518

Fax:  (256) 582-3548

Fax:  (205) 556-2701





Northwest Region

West Central and Southeast Region

Angie James, RN, BSN

Sharon Bradford, RN, BSN

Colbert County Health Department

Bibb County Health Department

P.O. Box 929

281 Alexander Avenue

Tuscumbia, Alabama  35674

Centerville, AL  35042 

Telephone:  (256) 389-3580 

Telephone:  (205) 926-9702

Fax:  (256) 383-8843

Fax:  (205) 926-6536 





Jefferson County


Yvette Burt, RN


Jefferson County Health Department


1400 6th Avenue South


Birmingham, Alabama  35233


Telephone:  (205) 930-1462


Fax:  (205) 930-1299



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