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Perinatal Hepatitis B Program

Serious Risk to Infants

Hepatitis B virus (HBV) infection in a pregnant woman poses a serious risk to her infant at birth. Without postexposure immunoprophylaxis, approximately 40% of infants born to HBV-infected mothers in the United States will develop chronic HBV infection, approximately one-fourth of whom will eventually die from chronic liver disease. Perinatal HBV transmission can be prevented by identifying HBV-infected (i.e., hepatitis B surface antigen [HBsAg]-positive) pregnant women and providing hepatitis B immune globulin and hepatitis B vaccine to their infants within 12 hours of birth. Preventing perinatal HBV transmission is an integral part of the national strategy to eliminate hepatitis B in the United States.

National Guidelines:

  • Universal screening of pregnant women for HBsAg during each pregnancy
  • Case management of HBsAg-positive mothers and their infants
  • Provision of immunoprophylaxis for infants born to infected mothers, including hepatitis B vaccine and hepatitis B immune globulin
  • Routine vaccination of all infants with the hepatitis B vaccine series, with the first dose administered at birth

Alabama Perinatal Hepatitis B Program Services

Perinatal Hepatitis B Coordinators serve public and private HBsAg-positive maternity patients throughout Alabama. They provide the following services at no charge to the patient or provider:

  • Patient education and counseling.
  • Identification and testing of household and sexual contacts including vaccination with hepatitis B vaccine if indicated.
  • Notification of the birth hospital about impending birth to ensure that HBIG and hepatitis B vaccine are available for the newborn in the first 12 hours of life.
  • Notification of the medical provider of the infant's birth and the hepatitis B vaccination schedule.
  • Follow-up of the infant to ensure the hepatitis B vaccine series is completed and the infant is tested for antibodies to hepatitis B to ensure the baby is protecte.

Perinatal Hepatitis B Program Coordinators

For referral and case management of HBsAg-positive maternity patients, complete VPD REPORT Card, contact the Perinatal Hepatitis B Coordinator below in your area, or call the Immunization Division at 1-800-469-4599.

Northeast Region

North Central Region

Anita Collier, RN

Rebecca Warren, RN, MSN

Marshall County Health Department

Tuscaloosa Co Health Department

Guntersville, Alabama  35976

Tuscaloosa, Alabama  35405

Telephone:  (256) 582-2390

Telephone:  (205) 554-4518

Fax:  (256) 582-3548

Fax:  (205) 556-2701



Northwest Region

West Central and Southeast Region

Angie James, RN, BSN

Sharon Bradford, RN, BSN

Colbert County Health Department

Bibb County Health Department

Tuscumbia, Alabama  35674

Centerville, AL  35042 

Telephone:  (256) 389-3580 

Telephone:  (205) 926-9702

Fax:  (256) 383-8843

Fax:  (205) 926-6536 



Jefferson County


Yvette Burt, RN


Jefferson County Health Department


Birmingham, Alabama  35233


Telephone:  (205) 930-1462


Fax:  (205) 930-1299



CDC and Immunization Action Coalition Resources

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