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Perinatal Hepatitis B Program

Serious Risk to Infants

Hepatitis B virus (HBV) infection in a pregnant woman poses a serious risk to her infant at birth. Without postexposure immunoprophylaxis, approximately 40% of infants born to HBV-infected mothers in the United States will develop chronic HBV infection, approximately one-fourth of whom will eventually die from chronic liver disease. Perinatal HBV transmission can be prevented by identifying HBV-infected (i.e., hepatitis B surface antigen [HBsAg]-positive) pregnant women and providing hepatitis B immune globulin and hepatitis B vaccine to their infants within 12 hours of birth. Preventing perinatal HBV transmission is an integral part of the national strategy to eliminate hepatitis B in the United States.

National Guidelines

  • Universal screening of pregnant women for HBsAg during each pregnancy
  • Case management of HBsAg-positive mothers and their infants
  • Provision of immunoprophylaxis for infants born to infected mothers, including hepatitis B vaccine and hepatitis B immune globulin
  • Routine vaccination of all infants with the hepatitis B vaccine series, with the first dose administered at birth

Alabama Perinatal Hepatitis B Program Services

Perinatal Hepatitis B Coordinators serve public and private HBsAg-positive maternity patients throughout Alabama. They provide the following services at no charge to the patient or provider:

  • Patient education and counseling.
  • Identification and testing of household and sexual contacts including vaccination with hepatitis B vaccine if indicated.
  • Notification of the birth hospital about impending birth to ensure that HBIG and hepatitis B vaccine are available for the newborn in the first 12 hours of life.
  • Notification of the medical provider of the infant's birth and the hepatitis B vaccination schedule.
  • Follow-up of the infant to ensure the hepatitis B vaccine series is completed and the infant is tested for antibodies to hepatitis B to ensure the baby is protecte.

Perinatal Hepatitis B Program Coordinators

For referral and case management of HBsAg-positive maternity patients, complete VPD REPORT Card, contact the Perinatal Hepatitis B Coordinator below in your area, or call the Immunization Division at 1-800-469-4599.

North Region

Jefferson County

Angie James, RN

Yvette Burt, RN

Colbert County Health Department

Jefferson County Health Department

Tuscumbia, Alabama 35674

Birmingham, Alabama  35233

Telephone: (256) 389-3580

Telephone: (205) 930-1462

Fax: (256) 383-8843

Fax: (205) 930-1299



Central Region

Montgomery County

Rebecca Warren, RN, MSN

Brenda Curenton, RN

Tuscaloosa Co Health Department

3060 Mobile Highway

Tuscaloosa, Alabama 35405

Montgomery, Alabama 36108

Telephone: (205) 554-4518

Telephone: (334) 293-6436

Fax: (205) 556-2701

Fax: (334) 293-6405



South Region


Sharon Bradford, RN, BSN


Bibb County Health Department


Centerville, AL 35042


Telephone: (205) 926-9702


Fax: (205) 926-6536


CDC and Immunization Action Coalition Resources

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